Rona G Giffard Selected Research

Antagomirs

1/2021	MicroRNA-338 inhibition protects against focal cerebral ischemia and preserves mitochondrial function in vitro in astrocytes and neurons via COX4I1.
1/2019	Pre-treatment with microRNA-181a Antagomir Prevents Loss of Parvalbumin Expression and Preserves Novel Object Recognition Following Mild Traumatic Brain Injury.
2/2015	Post-stroke treatment with miR-181 antagomir reduces injury and improves long-term behavioral recovery in mice after focal cerebral ischemia.
2/2015	MicroRNA-200c contributes to injury from transient focal cerebral ischemia by targeting Reelin.
12/2013	Inhibition of microRNA-181 reduces forebrain ischemia-induced neuronal loss.

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Rona G Giffard Research Topics

Disease

30	Ischemia 07/2019 - 10/2002
23	Stroke (Strokes) 01/2021 - 05/2002
23	Brain Ischemia (Cerebral Ischemia) 12/2017 - 08/2002
13	Infarction (Infarctions) 01/2021 - 05/2002
12	Inflammation (Inflammations) 01/2018 - 05/2002
9	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2021 - 05/2007
8	Brain Injuries (Brain Injury) 02/2015 - 04/2005
5	Hypothermia 02/2009 - 01/2002
3	Ischemic Stroke 12/2017 - 10/2011
3	Necrosis 03/2013 - 12/2002
2	Hemorrhage 04/2017 - 04/2006
2	Hypoxia (Hypoxemia) 08/2006 - 11/2002
2	Neurodegenerative Diseases (Neurodegenerative Disease) 08/2005 - 08/2004
1	Brain Concussion (Cerebral Concussion) 01/2019
1	Neuroinflammatory Diseases 01/2019
1	Seizures (Absence Seizure) 12/2017
1	Glioblastoma (Glioblastoma Multiforme) 04/2017
1	Retinoblastoma (Glioblastoma, Retinal) 01/2017
1	Brain Infarction 02/2015
1	Transient Ischemic Attack 02/2015
1	Ear Diseases (Disease, Ear) 08/2013
1	Ototoxicity 08/2013
1	Infections 03/2013
1	Brain Neoplasms (Brain Tumor) 03/2013
1	Mitochondrial Diseases (Mitochondrial Disease) 03/2012
1	Tibial Fractures (Fracture, Tibial) 04/2011
1	Memory Disorders (Memory Loss) 04/2011
1	Sepsis (Septicemia) 03/2011
1	Heart Arrest (Cardiac Arrest) 07/2010

Drug/Important Bio-Agent (IBA)

11	MicroRNAs (MicroRNA)IBA 07/2019 - 01/2012
7	CytokinesIBA 01/2018 - 04/2005
7	Heat-Shock Proteins (Heat-Shock Protein)IBA 08/2013 - 10/2002
6	Proteins (Proteins, Gene)FDA Link 11/2014 - 08/2004
6	Glucose (Dextrose)FDA LinkGeneric 03/2012 - 10/2003
5	AntagomirsIBA 01/2021 - 12/2013
5	Oxygen (Dioxygen)IBA 05/2008 - 10/2003
3	triphenyltetrazoliumIBA 08/2015 - 01/2009
3	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 02/2014 - 10/2003
3	salicylhydroxamic acid (SHAM)IBA 03/2013 - 08/2002
3	Free RadicalsIBA 02/2009 - 10/2002
3	Adenosine Triphosphate (ATP)IBA 05/2008 - 09/2004
2	Protein Kinases (Protein Kinase)IBA 01/2017 - 06/2013
2	Interleukin-4 (Interleukin 4)IBA 08/2015 - 07/2011
2	Messenger RNA (mRNA)IBA 02/2015 - 03/2013
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2015 - 05/2008
2	HSP72 Heat-Shock ProteinsIBA 12/2012 - 08/2008
2	Endoplasmic Reticulum Chaperone BiPIBA 01/2012 - 03/2011
2	Molecular Chaperones (Chaperone, Molecular)IBA 01/2012 - 03/2004
2	Minocycline (Cyclops)FDA LinkGeneric 12/2010 - 04/2006
2	NF-kappa B (NF-kB)IBA 02/2009 - 08/2006
2	Phosphotransferases (Kinase)IBA 02/2009 - 01/2002
2	ChaperoninsIBA 05/2007 - 04/2006
2	Superoxide DismutaseIBA 08/2006 - 04/2005
2	CopperIBA 08/2006 - 04/2005
2	ZincIBA 08/2006 - 04/2005
2	CaspasesIBA 06/2005 - 05/2003
2	LipopolysaccharidesIBA 04/2005 - 05/2002
2	Apoptosis Regulatory ProteinsIBA 09/2004 - 05/2003
2	Cytochromes c (Cytochrome c)IBA 05/2003 - 01/2002
1	ParvalbuminsIBA 01/2019
1	Oxytocin (Pitocin)FDA LinkGeneric 01/2019
1	Hormones (Hormone)IBA 01/2019
1	Anesthetics (Anesthetic Agents)IBA 12/2017
1	CateninsIBA 04/2017
1	Adenosine Monophosphate (AMP)IBA 01/2017
1	Capsules (Microcapsules)IBA 01/2017
1	Estrogen ReceptorsIBA 01/2017
1	InterleukinsIBA 08/2015
1	Reelin ProteinIBA 02/2015
1	Therapeutic UsesIBA 02/2015
1	X-Linked Inhibitor of Apoptosis ProteinIBA 02/2015
1	Peptides (Polypeptides)IBA 06/2013
1	glucose-regulated proteinsIBA 03/2013
1	Interleukin-6 (Interleukin 6)IBA 03/2013
1	Ataxin-3IBA 03/2013
1	OrexinsIBA 03/2013
1	VimentinIBA 12/2012
1	Biological ProductsIBA 09/2012
1	Adrenergic Receptors (Adrenergic Receptor)IBA 09/2012
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 09/2012
1	CalciumIBA 01/2012
1	NADP (NADPH)IBA 10/2011
1	Oxidoreductases (Dehydrogenase)IBA 10/2011
1	acetovanillone (apocynin)IBA 10/2011
1	Transcription Factors (Transcription Factor)IBA 07/2011
1	Peroxidase (Myeloperoxidase)IBA 07/2011
1	Isoflurane FDA LinkGeneric 04/2011
1	Toll-Like Receptor 4IBA 03/2011
1	Bromodeoxyuridine (BrdU)IBA 01/2011
1	mortalinIBA 09/2010
1	cresyl violetIBA 01/2009
1	ICI 118551IBA 01/2009
1	Neuroprotective AgentsIBA 01/2009
1	beta Adrenergic ReceptorsIBA 01/2009
1	Aspartic Acid (Aspartate)FDA Link 08/2007

Therapy/Procedure

9	Therapeutics 01/2021 - 05/2002
1	Intraventricular Infusions 02/2015
1	Anesthesia 04/2011
1	Resuscitation 07/2010
1	Sutures (Suture) 01/2009